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ExomesGenomesTotal
Filters No dataPassNot in exomes
Allele Count-114272114272
Allele Number-151822151822
Allele Frequency-0.75270.7527
Grpmax Filtering AF
(95% confidence)
-0.9218
African/African American
0.9218
African/African American
Number of homozygotes-4418244182

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Genetic Ancestry Group Frequencies

Note Local ancestry data is available for this variant by selecting the tab below. See our blog post on local ancestry inference for Admixed American samples in gnomAD for more information.

3856541486179390.9296
4261479418990.8888
159620966200.7615
111751523640960.7335
251134709220.7236
3705514413550.7203
209294770.7109
4587567940154880.6752
6079102050.6670
57681045215810.5519
XX5870577672227330.7558
XY5556774150214490.7494
Total114272151822441820.7527
Include:

Related Variants

Liftover

The following GRCh37 variant lifts over to this variant:

Variant Effect Predictor

This variant falls on 0 transcripts in 0 genes.

Note The gene symbols shown below are provided by VEP and may differ from the symbol shown on gene pages.

    In Silico Predictors

    • CADD: 1.86
    • phyloP: -1.75
    Note For more detailed and up to date SpliceAI and Pangolin predictions, please visit our SpliceAI Lookup browser

    Genomic Constraint of Surrounding 1kb Region

    Genomic constraint values displayed are for the region: 6-134905000-134906000

    Read more about this constraint.

    ExpectedObservedConstraint
    228.1308Z = -5.29
    o/e = 1.35
    Z Score not constrainedconstrained2.184.0

    View the genomic constraint values for the 40kb region surrounding this variant: 6-134885951-134925951

    Age Distribution

    • Exome
    • Genome
    • Variant carriers
    • All individuals
    < 3030-3535-4040-4545-5050-5555-6060-6565-7070-7575-80> 80Age05001.00K1.50K2.00K2.50K3.00K3.50K4.00KVariant carriers05001.00K1.50K2.00K2.50K3.00K3.50K4.00KAll individuals

    Genotype Quality Metrics

    • Exome
    • Genome
    • Variant carriers
    • All individuals
    0-510-1520-2530-3540-4550-5560-6570-7580-8590-95> 100Genotype quality05.00K10.0K15.0K20.0K25.0K30.0K35.0K40.0KVariant carriers05.00K10.0K15.0K20.0K25.0K30.0K35.0K40.0KAll individuals

    Site Quality Metrics

    • Exome
    • Genome
    1e11e1.51e21e2.51e31e3.51e41e4.51e51e5.51e61e6.51e71e7.51e81e8.51e91e9.51e10SiteQuality0100K200K300K400K500K600K700K800K900K1.00M1.10M1.20MGenome variants1.146e+8

    Value: 1.146e+8 (genome samples)

    Site quality approximation for all variants with AF >= 0.5.

    Note: These are site-level quality metrics, they may be unpredictable for multi-allelic sites.

    Read Data


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